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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAPK3 All Species: 22.73
Human Site: S50 Identified Species: 45.45
UniProt: O43293 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43293 NP_001339.1 454 52536 S50 F I K K R R L S S S R R G V S
Chimpanzee Pan troglodytes XP_001140200 1430 160025 K50 F I K K R R T K S S R R G V S
Rhesus Macaque Macaca mulatta XP_001101129 454 52535 S50 F I K K R R L S S S R R G V S
Dog Lupus familis XP_533950 454 52750 S50 F I K K R R L S S S R R G V S
Cat Felis silvestris
Mouse Mus musculus O54784 448 51403 P50 F I K K R R L P S S R R G V S
Rat Rattus norvegicus O88764 448 51431 P50 F I K K R R L P S S R R G V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517613 524 60252 S120 F I K K R R L S S S R R G V S
Chicken Gallus gallus NP_001026784 974 109076 K50 F I K K R R T K S S R R G V G
Frog Xenopus laevis NP_001089464 452 52318 S50 F I K K R R L S S S R R G V S
Zebra Danio Brachydanio rerio XP_690685 453 52525 S50 F I K K R R L S S S R R G V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q0KHT7 784 85666 A74 F L K R R R R A Q S S D K E I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWL2 534 60474 I122 S I S K R K L I R R K D I E D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.9 98.9 95.3 N.A. 83.9 83.6 N.A. 76.1 34 78.1 80.4 N.A. 22.5 N.A. N.A. N.A.
Protein Similarity: 100 29.2 99.7 97.8 N.A. 90.9 90.7 N.A. 81.6 40.9 89.2 90.9 N.A. 35.4 N.A. N.A. N.A.
P-Site Identity: 100 86.6 100 100 N.A. 93.3 93.3 N.A. 100 80 100 100 N.A. 33.3 N.A. N.A. N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 93.3 93.3 N.A. 100 80 100 100 N.A. 53.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 45.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % E
% Phe: 92 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 84 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 92 0 0 0 0 0 9 0 0 0 0 9 0 9 % I
% Lys: 0 0 92 92 0 9 0 17 0 0 9 0 9 0 0 % K
% Leu: 0 9 0 0 0 0 75 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 100 92 9 0 9 9 84 84 0 0 0 % R
% Ser: 9 0 9 0 0 0 0 50 84 92 9 0 0 0 75 % S
% Thr: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 84 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _